October 27, 2015

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Methyl cobalamin

Chemical Formula: C63H91CoN13O14P

CAS No. 13422-55-4

Description:

Methyl cobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin. It differs from cyan cobalamin in that the cyanide is replaced by amethyl group.[1] Methylcobalamin features an octahedral cobalt(III) center. Methylcobalamin can be obtained as bright red crystals.[2] From the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal-alkyl bonds. Nickel-methyl intermediates have been proposed for the final step of methanogenesis.

Methylcobalamin is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lack of vitamin B12 (vitamin B12 deficiency), such as pernicious anemia.
Methylcobalamin is also used in the treatment of neuropathy, diabetic, and as a preliminary treatment for amyotrophic lateral

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